Thiocolchicoside

Description

Gloriosa superba is also known as the flame lily, contains a compound called colchicine which is used for the treatment of gout. Thiocolchicoside is a synthetic derivative of colchicine, that has been used clinically for a long time as a muscle relaxant, anti-inflammatory, and analgesic. Thiocolchicoside is a GABA-A receptor antagonist, so it binds to GABA-A and strychnine sensitive glycine receptor which result in muscle relaxation. Thiocolchicoside is rapidly adsorbed after oral administration and metabolized in the intestines and circulation.

Please get information pharmaceutical products.

Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals.

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